Memoirs of the Department of Agriculture in India. (Veterinary Series) Kumri - Combined Diffuse Sclerosis and Central Poliomyelitis of Horses June 1917

The author distinguished the Burmese from the Indian type of kumri, regarding the latter as acute rheumatism of the muscles of the back and loins, or congestion of the coverings of the spinal cord ; whereas, cases of the former at autopsy showed amyloid changes of liver and kidney and, during life, had incontinence of mine as an invariable symptom. [...] It would be out of place here to give any exhaustive account of the various clinical manifestations of the disease, but the main characteristics of a typical case are described, as a consideration of the appearances presented has an important evidential value in determining the type of paralysis present and the probable nature of the underlying pathological lesion. [...] In the case of the filarke which show diurnal periodicity, there is also a cyclic variation in the number of eosinopbiles corresponding with the times when the embryos swarm in the peripheral blood. [...] The plant is harmless in the early stages of growth, but becomes toxic at the time of the formation of seeds ; the seeds themselves are the most toxic part. [...] In this case the microbe might legitimately be called the predisposing, the external circumstances the immediate cause of the disorder ; there is nothing in such terminology incon- sistent with the intimate causal relationship of the bacterium with the morbid phenomenon and the remoter ancillary functions of the extraneous conditions.