cover image: The Indian Medical Gazette. A Monthly Journal of Medicine  Surgery  Public Health  and General Medical Intelligence  Indian and European. April 1947

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The Indian Medical Gazette. A Monthly Journal of Medicine Surgery Public Health and General Medical Intelligence Indian and European. April 1947

1947

The classical work of Castle and his associates (1929 1930 1931) demonstrated that Addisonian pernicious anemia was due to the lack of the intrinsic factor in the gastric juice and established the supreme role of the stomach in the pathogenesis of this anemia. [...] Fox and Castle (1942) have proved that the site of secretion of the intrinsic factor as defined by the ha3mopoietic activity of the human stomach preparations corresponded to the site of degenerative processes in the stomach (the fundus and the cardia but not the pylorus or the duodenum) in Addisonian pernicious anemia. [...] The lack of the intrinsic factor of Castle responsible for Addisonian pernicious anemia therefore has an underlying structural basis— tin atrophy of the acid-secreting area of the stomach which is also the site of secretion of the human intrinsic factor. [...] There was pallor of the skin and the mucose and brownish pigmenttion over the forehead and the dorsum of the hands and feet. [...] Histologically the stomach showed the condtion of chronic gastritis : a diminution in the parenchymatous elements of the mucosa fibrosis and presence of chronic inflammatory cellular accumulations in the mucosa and the sumucosa.
technology medicine science
Pages
87
Published in
India
SARF Document ID
sarf.120338
Segment Pages Author Actions
Frontmatter
179-180 S.D.S. Greval view
Some Observations Regarding the Toxicity of Thiamin Chloride and Nicotinic Acid
181-182 S. H. Zaidi view
The Gastric Mucosa in Tropical Macrocytic Anemia Report of A Case
182-186 J. C. Patel, Y. M. Bhende view
A Study on Clinical Value of the Widal Reaction and its Variations in Typhoid Fever
186-189 K. U. Jhatakia view
Stibanate (Sodium Antimony Gluconate) with Pedun Culine in the Treatment of Kala-Azar
189-190 Subodh Sanyal view
The Incidence and Causation of Glycosuria in Pregnancy
191-193 K. C. Batliwalla view
Parenteral Quinacrine in Malarial Fevers
193-195 K. L. Basumullick, J. C. Gupta view
Incidence of Malaria in Calcutta City
195-199 S. Sen, B. C. Basu view
Phenyl Cellosolve in the Treatment of Pediculosis
199-200 D. N. Roy, S. M. Ghosh view
Sporotrichosis of the Skin in India (A New Species Described)
200-202 D. Panja, N. C. Dey, L. M. Ghosh view
Serological Technique (Contd.)
202-203 S. D. S. Greval view
Intussusception Following Infolding of Bowel
203-206 N. S. Macpherson, E. W. Gault view
A Mirror of Hospital Practice
206-209 S.D.S. Greval view
Therapeutic Notes
209-212 S.D.S. Greval view
India Medical Gazette
213-215 S.D.S. Greval view
Medical News
215-218 S.D.S. Greval view
Public Health Section
219-225 S.D.S. Greval view
India Medical Gazette Fifty Years Ago
225-227 S.D.S. Greval view
Current Topics Etc.
227-239 S.D.S. Greval view
Reviews
239-239 S.D.S. Greval view
Book Recived
240-240 S.D.S. Greval view
Abstracts from Reports
240-241 S.D.S. Greval view
Correspondence
241-241 S.D.S. Greval view
Service Notes
242-244 S.D.S. Greval view

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